Contact Us
TEL: +86-571-86217390
E-mail: sales@gihichemicals.com
Address: No.7, Huacai International Building, Dengcai Road, Sandun, Westlake District, Hangzhou, Zhejiang
Factory links: www.gihichem.com

544-31-0

Technical Data Sheet TD NO:GH-T-01 Basic Information Product Quality

  • Features & Specification

    Technical Data Sheet

    TD NO:GH-T-01


    Basic Information

    Product Name

    Palmitoylethanolamide

    Synonym

    N-(2-HYDROXYETHYL)HEXADECANAMIDE;N-HEXADECANOYLETHANOLAMINE;PEA   PALMIDROL;PALMITYLETHANOLAMIDE;PALMITOYLETHANOLAMIDE;PALMITOYLETHANOLAMIDE N-(2-HYDROXYETHYL)HEXADECANAMIDE;N-(2-Hydroxyethyl)-Hexadecanamid;Palmidrol

    Product No

    GIHI-01

    Formula

    C18H37NO2

    Molecular Weight

    299.49

    CAS NO

    544-31-0

    EINECS  NO

    208-867-9

    Melting Point

    97-98℃

    Structure

    image003.gif


    Product Quality

    No

    Item

    Specification

    1

    Appearance

    White powder

    2

    Water

    0.5% max

    3

    Storage

    Stable under   recommended storage conditions.

    4

    instruction

    Palmitoylethanolamide   (PEA) is an endogenous fatty acid amide, belonging to the class of nuclear   factor agonists. PEA has been demonstrated to bind to a receptor in the   cell-nucleus (a nuclear receptor) and exerts a great variety of biological   functions related to chronic pain and inflammation. The main target is   thought to be the peroxisome proliferator-activated receptor alpha   (PPAR-α).[2][3] PEA also has affinity to cannabinoid-like G-coupled receptors   GPR55 and GPR119.[4] PEA cannot strictly be considered a classic   endocannabinoid because it lacks affinity for the cannabinoid receptors CB1   and CB2.[5] However, the presence of PEA (and other structurally related   N-acylethanolamines) has been known to enhance anandamide activity by an   "entourage effect".[6][7] Several papers have demonstrated that an   imbalance of the endocannabinoid system (ECS) and alterations in the levels   of PEA occur in acute and chronic inflammation.[8] For instance, during   β-amyloid-induced neuroinflammation the deregulation of cannabinoid receptors   and their endogenous ligands accompanies the development and progression of   disease.[9] PEA has been shown to have anti-inflammatory,[3]   anti-nociceptive,[10] neuroprotective,[11] and anticonvulsant properties


Hot Tags: 544-31-0, China, suppliers, manufacturers, factory, wholesale
Related Products
Inquiry